Volume 134, Issue 4 p. 609-612
Original Research

The Impact of Atopy, Sinus Opacification, and Nasal Patency on Quality of Life in Patients with Severe Nasal Polyposis

Isam Alobid MD, PhD

Corresponding Author

Isam Alobid MD, PhD

Rhinology Unit, Department of Otorhinolaryngology (ICEMEQ), Catalunya, Spain

Reprint requests: Isam Alobid, MD, PhD, Rhinology Unit, Department of Otorhinolaryngology, Hospital Clinic i Universitari, c/Villarroel, 170, Barcelona 08036, Spain. E-mail address: [email protected]Search for more papers by this author
Pedro Benítez MD, PhD

Pedro Benítez MD, PhD

Rhinology Unit, Department of Otorhinolaryngology (ICEMEQ), Catalunya, Spain

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Antonio Valero MD, PhD

Antonio Valero MD, PhD

Allergy Unit, Department of Pneumology and Allergy, Catalunya, Spain

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Joan Berenguer MD

Joan Berenguer MD

Department of Radiology, Catalunya, Spain

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Manuel Bernal-Sprekelsen MD, PhD

Manuel Bernal-Sprekelsen MD, PhD

Rhinology Unit, Department of Otorhinolaryngology (ICEMEQ), Catalunya, Spain

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Cesar Picado MD, PhD

Cesar Picado MD, PhD

Universtat de Barcelona, Catalunya, Spain

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Joaquim Mullol MD, PhD

Joaquim Mullol MD, PhD

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clinic, Department of Medicine, Catalunya, Spain

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First published: 17 May 2016
Citations: 6

Supported in part by grants from Generalitat de Catalunya (2001SGR00384) and Red RESPIRA (ISCiii-RTIC-03/11). Dr Isam Alobid is the 2004 recipient of the First Prize for Clinical Research presented by the European Rhinology Society.

Abstract

OBJECTIVES

Nasal polyposis has a great impact on the quality of life. The aim of this study was to evaluate the association between quality of life and atopy, sinus opacification, and nasal patency in severe nasal polyposis.

METHODS

One hundred nine patients completed the Medical Outcome Study Short Form-36 (SF-36) survey. Symptoms, polyp size, atopy, nasal patency, and sinus opacification were also scored.

RESULTS

Patients showed worse scores in all SF-36 domains, except for physical functioning, compared with Spanish population. Atopic patients had worse scores in role physical, body pain, vitality, and mental health than nonatopic patients. Atopic patients showed lower physical component summary (44.7 ± 1.1) and mental component summary (38.4 ± 1.0) than nonatopic patients (48.3 ± 1.6, 40.6 ± 1.3; P < 0.05), respectively. There were no correlations between quality of life and symptoms, polyp size, CT scan, nasal patency, and atopy.

CONCLUSION

Nasal polyposis has a considerable impact on quality of life and atopy worsens this impact.

EBM rating

C-4